Symbol
Name
ID

Neurog3
neurogenin 3
MGI:893591

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Type I diabetes mellitus	Type II diabetes mellitus
Disease(s) Associated with NEUROG3	Type I diabetes mellitus	Type II diabetes mellitus
congenital malabsorptive diarrhea 4
type 2 diabetes mellitus

Mouse Phenotypes

abnormal pancreatic acinar cell morphology

pancreatic acinar cell zymogen granule accumulation

abnormal small intestine crypts of Lieberkuhn morphology

abnormal endocrine pancreas morphology

abnormal pancreatic islet morphology

abnormal pancreatic alpha cell morphology

absent pancreatic alpha cells

abnormal pancreatic beta cell morphology

absent pancreatic beta cells

abnormal pancreatic delta cell morphology

absent pancreatic islets

small pancreatic islets

abnormal pancreas development

Availability

Mouse Genotype

Neurog3^tm1(EGFP)Khk/Neurog3^tm1(EGFP)Khk

Neurog3^tm1Fgu/Neurog3^tm1Fgu

Neurog3^tm1Heed/Neurog3^tm1Heed

Tg(Pdx1-Neurog3)1Heed/?

Neurog3^tm3.1Ggr/Neurog3^tm3.1Ggr
Tg(Vil1-cre)20Syr/0 (conditional)

Neurog3^tm1Fgu/Neurog3^tm3.1Ggr
Tg(Vil1-cre)20Syr/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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